Start research brachytherapy for better predictive models and safety

“I am very glad to receive the KWF Bas Mulder Award. This research grant will be essential to develop a novel system to improve patient safety and brachytherapy treatments.”

This is Gabriel Paiva Fonseca’s response to the grant from the Alpe d’HuZes / KWF fund. As a researcher of Maastro in this project he will be investigating a new system for brachytherapy.

High precision

Brachytherapy is successful in treating a wide variety of cancers as it is capable of delivering high radiation doses to the tumour resulting in good treatment outcome. Gabriel Paiva Fonseca: “This type of treatment requires high precision when placing a radioactive source inside or close to the tumour to avoid harming healthy tissue.”

Novel system for dosimetry

This project will develop a novel system for dosimetry (called IrIS – Iridium Imaging System), which is capable of verifying all relevant treatment parameters in real time, measuring the truly delivered dose the patient. “It is the first system that will use the treatment Ir-192 source for gamma-imaging, combining anatomical and dosimetric information. This is possible due to recent developments in imaging panel, patient tracking and 3D printing. Dosimetric and imaging data acquired during the treatment will be used to quantify organ/implant motion providing information not currently available.”

Novel idea

This novel idea will combine interdisciplinary cutting-edge technology to create a complete solution for treatment verification and imaging. “We expect that once this system is available and delivered dose known it will become the standard of care for all brachytherapy treatment due to the improved outcome assessment, better predictive models, and safety. Gabriel Paiva Fonseca will combine his research with a patient study of 100 patients with gynecological tumors and prostate cancer.”