Maastro Physics Research

In Maastro clinic research is performed on a wide range of topics in radiotherapy physics. Many of the topics are related to improving patient imaging by conducting research into PET-CT imaging, ultrasound imaging, novel CT imaging and small animal pre-clinical imaging. Other topics include brachytherapy dose calculations and particle beam radiotherapy. The research facilities include clinical linear accelerators, treatment planning systems, a small animal radiotherapy system, CT and PET-CT scanners, ultrasound imaging equipment, various devices for measuring radiation dose, simulation software for dose calculations and imaging, and an electronic brachytherapy source.


In the field of clinical radiation physics several research projects are ongoing. One main line of projects is “In Dose Guided Radiotherapy”. The aim of Dose-Guided Radiotherapy is accurate measurement of the true dose delivered to the patient. The 2D and 3D in-vivo dose verification checks the actual dose delivered to the patient before and during treatment using the exit-dose electronic portal imaging and dosimetry (EPID) measurement. We are also investigating the use of 3D ultrasound imaging for treatment verification.

Other projects are in Molecular Imaging where we develop new techniques to improve functional imaging with PET scanners, in particular for lung and rectal cancer patients. In Brachytherapy we work towards improved dose delivery for prostate cancer patients by developing advanced dose calculations, verification and imaging. Monte Carlo dose calculations are used heavily. In Particle Therapy we collaborate in a large European project to develop methods for imaging in particle beams. In Small Animal Radiotherapy Research we develop a novel research platform for precise treatment of small animals.


Several physicists are involved in teaching students from programs in engineering, physics, and medicine. There is also involvement in international teaching courses such as ESTRO and the Royal Marsden Radiotherapy course.

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