Cancer types
  • Lung
  • Mamma
Title of study
Exploratory study on nasal high flow therapy for breath hold in radiotherapy
Version Number
Approval Date 
2.4, 10 December 2018
Short Title
Study site
Principle Investigator
S. Peeters
Investigator Maastro
S. Peeters
Trial registry

The objective of this study is to investigate the feasibility of treating breast and lung cancer patients in mDIBH using nasal a high-flow therapy (NHFT) device

Primary Endpoint 

Proportion of patients completing the whole treatment with NHFT

Secondary Endpoints 

• Proportion of patients holding their breath 90 seconds during the training session
• Intrafraction and interfraction stability and reproducibility of NHFT supported mDIBH
• Subjective tolerance of mDIBH with NHFT
• Dose difference to surrounding normal tissues between standard plan and plan in mDIBH with NHFT