Cancer types
  • Digestive tract
Title of study
Transarterial Chemoembolization with Drug-Eluting Beads (standard arm) versus Stereotactic Body Radiation Therapy (experimental arm) for hepatocellular carcinoma
Version Number
Approval Date 
1.2, 11 May 2015
Short Title
Trendy
Study site
Principle Investigator
A. Méndez Romero MD, PhD (PI) Department of Radiation Oncology Erasmus MC Cancer Institute; A. Moelker MD, PhD (co-PI) Department of Radiology Erasmus MC
Investigator Maastro
Dr. J. Buijsen
Sponsor
Erasmus MC
WHO Trial Registry
DUCG
ClinicalTrials.gov
Objectives 

To assess the time to progression after TACE-DEB and after SBRT in a comparable po;ulation of paitents diagnosed with HCC

Primary Endpoint 

Time to progression, defined as time from randomization to radiological progression

Secondary Endpoints 

• Time to local recurrence
• Response rate (complete and partial)
• Overall survival
• Toxicity
• Quality of life